BDBM50578627 CHEMBL4872488

SMILES Clc1ccc(NC(=O)C[C@H]2CC[C@H](CC2)c2ccccc2)cc1

InChI Key InChIKey=LLEWXHXSCAAZRI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50578627   

TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578627(CHEMBL4872488)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human His-tagged IDO1 (Ala2 to Gly403 residues) expressed in Escherichia coli using tryptophan as substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50578627(CHEMBL4872488)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of IDO1 in human HeLa cells using tryptophan as substrate incubated for 24 hrs by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed