BDBM50578383 CHEMBL4870813

SMILES Cc1nonc1C(=O)N[C@@H](C1CCC(F)(F)CC1)c1nc2c(F)c(ccc2[nH]1)[C@H](CC(F)(F)F)c1nnc2ccc(cn12)C#N

InChI Key InChIKey=OXISIPGDBSNEQE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50578383   

TargetInterleukin-17A(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50578383(CHEMBL4870813)
Affinity DataIC50: 1nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed