BDBM50578350 CHEMBL4874549

SMILES CC(C)(C)Nc1nc(N[C@H]2CC[C@H](O)CC2)ncc1C(N)=O

InChI Key InChIKey=BLWZIEOGNLHMEX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50578350   

TargetMitogen-activated protein kinase 8(Mouse)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50578350(CHEMBL4874549)
Affinity DataIC50: 350nMAssay Description:Inhibition of JNK1 in mouse RAW264.7 cells assessed as inhibition of c-Jun phosphorylation incubated for 30 mins by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50578350(CHEMBL4874549)
Affinity DataIC50: 13nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50578350(CHEMBL4874549)
Affinity DataIC50: 18nMAssay Description:Inhibition of JNK2 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed