BDBM50578172 CHEMBL4855886::US12291516, Example 90

SMILES CC#CC(=O)N1CCCC[C@H]1c1nc(c(C(N)=O)n1N)-c1ccc(cc1)C(=O)Nc1cc(I)ccn1

InChI Key InChIKey=RKUNGXOSUGLQJY-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50578172   

TargetTyrosine-protein kinase BTK(Human)
Henan Normal University

Curated by ChEMBL
LigandPNGBDBM50578172(CHEMBL4855886 | US12291516, Example 90)
Affinity DataIC50: 11nMAssay Description:Inhibition of full-length N-terminal GST tagged BTK (2 to 659 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Henan Normal University

Curated by ChEMBL
LigandPNGBDBM50578172(CHEMBL4855886 | US12291516, Example 90)
Affinity DataIC50: 10.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Henan Normal University

Curated by ChEMBL
LigandPNGBDBM50578172(CHEMBL4855886 | US12291516, Example 90)
Affinity DataIC50: 10.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent

TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Henan Zhiwei Biomedicine

US Patent
LigandPNGBDBM50578172(CHEMBL4855886 | US12291516, Example 90)
Affinity DataIC50: 226nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Henan Normal University

Curated by ChEMBL
LigandPNGBDBM50578172(CHEMBL4855886 | US12291516, Example 90)
Affinity DataIC50: 10.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase ITK/TSK(Human)
Henan Zhiwei Biomedicine

US Patent
LigandPNGBDBM50578172(CHEMBL4855886 | US12291516, Example 90)
Affinity DataIC50: 532nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Henan Normal University

Curated by ChEMBL
LigandPNGBDBM50578172(CHEMBL4855886 | US12291516, Example 90)
Affinity DataIC50: 10.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Henan Zhiwei Biomedicine

US Patent
LigandPNGBDBM50578172(CHEMBL4855886 | US12291516, Example 90)
Affinity DataIC50: 4.68E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent