BDBM50578146 CHEMBL4868899::US12291516, Example 77

SMILES CCc1ccnc(NC(=O)c2ccc(cc2)-c2nc([C@@H]3CCCCN3C(=O)C#CC)n(N)c2C(N)=O)c1

InChI Key InChIKey=FJXWWDSJINEECO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50578146   

TargetTyrosine-protein kinase BTK(Human)
Henan Normal University

Curated by ChEMBL
LigandPNGBDBM50578146(CHEMBL4868899 | US12291516, Example 77)
Affinity DataIC50: 18nMAssay Description:Inhibition of full-length N-terminal GST tagged BTK (2 to 659 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Henan Normal University

Curated by ChEMBL
LigandPNGBDBM50578146(CHEMBL4868899 | US12291516, Example 77)
Affinity DataIC50: 17.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2025
Entry Details
Go to US Patent