BDBM50577688 CHEMBL4875545

SMILES CC(=O)c1ccc(NS(=O)(=O)c2cccc(c2)-c2n[nH]c3cc(F)ccc23)cc1

InChI Key InChIKey=WQCBLPJCIOITFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50577688   

TargetDual specificity mitogen-activated protein kinase kinase 4(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50577688(CHEMBL4875545)
Affinity DataIC50: 860nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50577688(CHEMBL4875545)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged MEK7 expressed in Sf21 cells using JNK1 as substrate pre-incubated for 30 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed