BDBM50577613 CHEMBL4857804
SMILES COC(=O)c1cn(C)c2ccc(cc12)-c1cccnc1
InChI Key InChIKey=CPJVLZDDECEONQ-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50577613
TargetNuclear receptor subfamily 4 group A member 2(Human)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inverse agonist activity at Gal4-fused human Nurr1 LBD expressed in HEK293T cells co-expressing firefly luciferase assessed as luciferase activity by...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 4 group A member 2(Human)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inverse agonist activity at Gal4-fused human Nurr1 LBD expressed in HEK293T cells co-expressing firefly luciferase assessed as luciferase activity in...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 4 group A member 2(Human)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 5.70E+4nMAssay Description:Inverse agonist activity at human Nurr1 LBD assessed as displacement of NCoR1 from Nurr1 after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 4 group A member 2(Human)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 2.90E+4nMAssay Description:Inverse agonist activity at human Nurr1 LBD assessed as displacement of NCoR2 from Nurr1 after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 4 group A member 2(Human)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inverse agonist activity at Gal4-fused human Nurr1 monomer response element NBRE expressed in HEK293T cells co-expressing firefly luciferase assessed...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 4 group A member 2(Human)
Goethe University Frankfurt
Curated by ChEMBL
Goethe University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inverse agonist activity at Nurr1 (unknown origin)More data for this Ligand-Target Pair