BDBM50577582 CHEMBL4852949

SMILES [H][C@@]1(OC[C@@H](CO1)NCc1cc2SCCOc2nn1)[C@@H](O)Cc1c(F)cnc2ccc(OC)nc12

InChI Key InChIKey=QUTCIOKBWBLIHI-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50577582   

TargetDNA gyrase subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50577582(CHEMBL4852949)
Affinity DataIC50: 220nMAssay Description:Inhibition of Staphylococcus aureus Gyrase supercoiling activity assessed as reduction in supercoiling pBR322 DNA by measuring relaxation by bromophe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50577582(CHEMBL4852949)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase IV decatenation activity using kDNA as substrate by ethidium bromide/bromophenol blue staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50577582(CHEMBL4852949)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50577582(CHEMBL4852949)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50577582(CHEMBL4852949)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50577582(CHEMBL4852949)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50577582(CHEMBL4852949)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50577582(CHEMBL4852949)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed