BDBM50577493 CHEMBL4865935

SMILES COc1nc(ccc1-n1cnc(C)c1)C1=NOCC(N1)c1ccccc1

InChI Key InChIKey=NCOBKTFWPFBTBX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50577493   

TargetPresenilin-1(Human)
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50577493(CHEMBL4865935)
Affinity DataEC50:  97nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50577493(CHEMBL4865935)
Affinity DataEC50:  97nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human wild type APP751 assessed as reduction in amyloid beta42 level incubated overnight b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed