BDBM50577488 CHEMBL4871972

SMILES Cc1nc(-c2cccc(F)c2O)n(CCc2ccccc2)c(=O)c1-c1ccc(CO)s1

InChI Key InChIKey=IKHPDBNPSSKDDD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50577488   

TargetNuclear receptor subfamily 1 group I member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50577488(CHEMBL4871972)
Affinity DataEC50:  1.30E+4nMAssay Description:Activation of full length human PXR expressed in human HepG2 cells co-expressing luciferase of CYP3A4 promoter transcription assessed as increase of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50577488(CHEMBL4871972)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human CaSR in human HEK293 cells measured after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed