BDBM50577486 CHEMBL4866041

SMILES CC1=C(C(=O)N(C(=N1)c2cccc(c2O)F)CCc3ccccc3)Cc4ccccc4

InChI Key InChIKey=BFDADFMMNADXMI-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50577486   

TargetNuclear receptor subfamily 1 group I member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50577486(CHEMBL4866041)
Affinity DataEC50:  1.00E+3nMAssay Description:Activation of full length human PXR expressed in human HepG2 cells co-expressing luciferase of CYP3A4 promoter transcription assessed as increase of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50577486(CHEMBL4866041)
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human CaSR in human HEK293 cells measured after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed