BDBM50577485 CHEMBL4859029

SMILES Cc1ccc(s1)-c1c(C)nc(-c2cccc(F)c2O)n(CCc2ccccc2)c1=O

InChI Key InChIKey=FOSZTBOMAKNEAC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50577485   

TargetExtracellular calcium-sensing receptor(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50577485(CHEMBL4859029)
Affinity DataIC50: 51nMAssay Description:Antagonist activity at mouse CaSRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50577485(CHEMBL4859029)
Affinity DataEC50:  2.50E+3nMAssay Description:Activation of full length human PXR expressed in human HepG2 cells co-expressing luciferase of CYP3A4 promoter transcription assessed as increase of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50577485(CHEMBL4859029)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human CaSR in human HEK293 cells measured after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed