BDBM50577458 CHEMBL4858437

SMILES B(CCC[C@@H]1CCN[C@@H]1C(=O)O)(O)O

InChI Key InChIKey=AMHQFAXDSRWEOU-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50577458   

TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50577458(CHEMBL4858437)
Affinity DataIC50: 16nMAssay Description:Inhibition of ARG1 (unknown origin) assessed as reduction in thio-ornithine production using thioarginine as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50577458(CHEMBL4858437)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant ARG1 expressed in Escherichia coli using thioarginine as a substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50577458(CHEMBL4858437)
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of human ARG1 in HEK293 cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed