BDBM50577453 CHEMBL4869861

SMILES COc1cccc(CNc2ccc(cc2)S(=O)(=O)Nc2nc3c(ccc4ccccc34)s2)c1O

InChI Key InChIKey=FGEYJIMYIDJKTF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50577453   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50577453(CHEMBL4869861)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 5-LOXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50577453(CHEMBL4869861)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human reticulocyte 15-LOX-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50577453(CHEMBL4869861)
Affinity DataIC50: 50nMAssay Description:Inhibition of wild type human N-terminal His-tagged 12-LOX using arachidonic acid as substrate by UV-Vis spectroscopy analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50577453(CHEMBL4869861)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human epithelial cell 15-LOX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed