BDBM50577194 CHEMBL4874448

SMILES CN1CCN(CC1)c1ccc(cc1)-c1cc2c(ncnc2s1)N1CCN(CC1)C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=ZYZUOYYVHYGMDE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50577194   

TargetVascular endothelial growth factor receptor 3(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50577194(CHEMBL4874448)
Affinity DataIC50: 110nMAssay Description:Inhibition of human FLT4/VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMisshapen-like kinase 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50577194(CHEMBL4874448)
Affinity DataIC50: 335nMAssay Description:Inhibition of human MINKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMaternal embryonic leucine zipper kinase(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50577194(CHEMBL4874448)
Affinity DataIC50: 700nMAssay Description:Inhibition of human MELKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50577194(CHEMBL4874448)
Affinity DataIC50: 718nMAssay Description:Inhibition of human BTKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50577194(CHEMBL4874448)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human KDR/VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50577194(CHEMBL4874448)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FLT1/VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed