BDBM50577119 CHEMBL4868596

SMILES C[C@@H](NC(=O)N1CCC(CC1)NC(=O)c1nccs1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC1CCCCC1)C(=O)[C@@]1(C)CO1

InChI Key InChIKey=NMAUQRZMJYEOQL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50577119   

TargetProteasome subunit beta type-8(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50577119(CHEMBL4868596)
Affinity DataIC50: 719nMAssay Description:Inhibition of human proteasome subunit beta-5i chymotrypsin like activity using SUC-ANW-AMC as flurogenic substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50577119(CHEMBL4868596)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20s proteasome beta 5c subunit using suc-WLA-AMC as flurogenic substrate preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed