BDBM50577117 CHEMBL4862242

SMILES C[C@@H](NC(=O)N1CCC(CC1)NC(=O)c1nccs1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1

InChI Key InChIKey=DFINWNNMGCBCLX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50577117   

TargetProteasome subunit beta type-8(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50577117(CHEMBL4862242)
Affinity DataIC50: 323nMAssay Description:Inhibition of human proteasome subunit beta-5i chymotrypsin like activity using SUC-ANW-AMC as flurogenic substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50577117(CHEMBL4862242)
Affinity DataIC50: 468nMAssay Description:Inhibition of chymotrypsin-like activity of human 20s proteasome beta 5c subunit using suc-WLA-AMC as flurogenic substrate preincubated for 15 mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed