BDBM50576852 CHEMBL4849098

SMILES Oc1ccccc1-c1nc(Cc2ccccc2)no1

InChI Key InChIKey=YYPDSPUGDQIDOX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50576852   

TargetThioredoxin reductase 1, cytoplasmic(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50576852(CHEMBL4849098)
Affinity DataIC50: 18nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetThioredoxin reductase 1, cytoplasmic(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50576852(CHEMBL4849098)
Affinity DataIC50: 18nMAssay Description:Inhibition of TrxR1 (unknown origin) assessed as reduction in DTNB to TNB by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50576852(CHEMBL4849098)
Affinity DataIC50: 16nMAssay Description:Inhibition of IKKalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50576852(CHEMBL4849098)
Affinity DataIC50: 16nMAssay Description:Inhibition of IKKalpha (unknown origin) by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50576852(CHEMBL4849098)
Affinity DataIC50: 22nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetNADPH oxidase 4(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50576852(CHEMBL4849098)
Affinity DataIC50: 22nMAssay Description:Inhibition of human NADPH oxidase 4 by quantitative sandwich enzyme immunoassay techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed