BDBM50576849 CHEMBL4876008

SMILES CCOC(=O)[C@@H](Cc1cn(C)c2ccccc12)NC(=O)[C@@H](N)CC(C)C

InChI Key InChIKey=WXTSKOFJNRRBHP-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50576849   

TargetCytochrome P450 3A4(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: 5.00E+3nMAssay Description:Direct inhibition of CYP3A4 in human hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP2D6 in human hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of CYP2C19 in human hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 in human hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2B6 in human hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C8 in human hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 in human hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of OATP1B3 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSolute carrier family 22 member 6(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of OAT1 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSolute carrier family 22 member 6(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of OAT3 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetPOU domain, class 2, transcription factor 1(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of OCT1 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetPOU domain, class 2, transcription factor 2(Human)
Newlink Genetics

Curated by ChEMBL
LigandPNGBDBM50576849(CHEMBL4876008)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of OCT2 (unknown origin) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed