BDBM50576722 CHEMBL4858766

SMILES Cn1cc(-c2ccc3nc(nc(N4CCOC[C@@H]4c4ccccc4)c3c2)-c2cnn(CC(C)(C)O)c2)c2cc[nH]c2c1=O

InChI Key InChIKey=DHRWSSOSGNJVOC-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576722   

TargetBromodomain-containing protein 4(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576722(CHEMBL4858766)
Affinity DataKd: <100nMAssay Description:Binding affinity to DNA-tagged human BRD4 (BD1,2) isoform long expressed in Escherichia coli BL21 incubated for 1 hr by competitive ligand binding BR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50576722(CHEMBL4858766)
Affinity DataIC50: 100nMAssay Description:Inhibition of binding of N-terminal His-tagged human full length recombinant BRD4 (2 to 1362 residues) expressed in baculovirus-infected Sf9 cells wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed