BDBM50576674 CHEMBL4850575

SMILES [H][C@]1(NC(=O)[C@H](CCCCNC(=N)NCCC[C@@H](NC(=O)[C@H](C)NC1=O)C(=O)N[C@@H](CCCCNC(=O)c1cnco1)C(N)=O)NC(=O)OCc1ccccc1)[C@H](C)O

InChI Key InChIKey=VFXVWVOWASHEBB-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50576674   

TargetProtein AF-9(Human)
The University of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50576674(CHEMBL4850575)
Affinity DataIC50: 410nMAssay Description:Inhibition of AF9 YEATS domain (1 to 138 residues) (unknown origin) assessed as inhibition of probe-1 induced AF9 YEATS domain labelling incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetProtein AF-9(Human)
The University of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50576674(CHEMBL4850575)
Affinity DataKd:  370nMAssay Description:Binding affinity to AF9 YEATS domain (1 to 138 residues) (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetProtein ENL(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50576674(CHEMBL4850575)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of ENL YEATS domain (unknown origin) by In-gel fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein ENL(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50576674(CHEMBL4850575)
Affinity DataKd:  1.41E+4nMAssay Description:Binding affinity to ENL YEATS domain (unknown origin) assessed as dissociation constant by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed