BDBM50576528 CHEMBL4859961

SMILES C1CCc2c(C1)c(nc1ccc3[nH]ncc3c21)-c1cn[nH]c1

InChI Key InChIKey=VAGPVIGSUDIGHA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50576528   

TargetCyclin-A1/Cyclin-dependent kinase 2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50576528(CHEMBL4859961)
Affinity DataIC50: 72nMAssay Description:Inhibition of CDK2/Cyclin A1 (unknown origin) at 1 uM using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50576528(CHEMBL4859961)
Affinity DataIC50: 90nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50576528(CHEMBL4859961)
Affinity DataIC50: 1.07E+4nMAssay Description:Displacement of F-c-di-GMP from human STING expressed in Escherichia coli Rosetta 2(pLysS) cells at 20 uM incubated for 5 mins by fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed