BDBM50576406 CHEMBL4848545

SMILES CC(N1CCC2(CCN(CC2)c2nc(C)cc(Nc3cc(C)[nH]n3)n2)C1=O)c1ccc(nc1)-n1cc(F)cn1

InChI Key InChIKey=MXDRPELFIWFPTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576406   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Guangzhou Baiyunshan Pharmaceutical Holdings

Curated by ChEMBL
LigandPNGBDBM50576406(CHEMBL4848545)
Affinity DataIC50: 74nMAssay Description:Inhibition of RET wild type (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Guangzhou Baiyunshan Pharmaceutical Holdings

Curated by ChEMBL
LigandPNGBDBM50576406(CHEMBL4848545)
Affinity DataIC50: 134nMAssay Description:Inhibition of RET V804M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed