BDBM50576401 CHEMBL4845703

SMILES C[C@H](N1CCCC2(CCC(CC2)c2nc(C)cc(Nc3cc(C)[nH]n3)n2)C1=O)c1ccc(nc1)-n1cc(F)cn1

InChI Key InChIKey=VLUBMNLERLEJHE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50576401   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Guangzhou Baiyunshan Pharmaceutical Holdings

Curated by ChEMBL
LigandPNGBDBM50576401(CHEMBL4845703)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of RET wild type (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Guangzhou Baiyunshan Pharmaceutical Holdings

Curated by ChEMBL
LigandPNGBDBM50576401(CHEMBL4845703)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of RET V804M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Guangzhou Baiyunshan Pharmaceutical Holdings

Curated by ChEMBL
LigandPNGBDBM50576401(CHEMBL4845703)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of RET M918T mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed