BDBM50576392 CHEMBL4879278

SMILES COc1cccc(CN2CCOc3cc(ccc3C2=O)-c2cnc3[nH]ccc3c2)c1

InChI Key InChIKey=VVURKQBQHYHEMC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50576392   

TargetRho-associated protein kinase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50576392(CHEMBL4879278)
Affinity DataIC50: 5.54E+3nMAssay Description:Inhibition of wild type partial length human ROCK1 (M1 to T431 residues) expressed in Mammalian expression system by Euro-fins kinase profiler assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50576392(CHEMBL4879278)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild type partial length human ROCK1 (M1 to R415 residues) expressed in mammalian expression system by Euro-fins kinase profiler assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50576392(CHEMBL4879278)
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant TNIK (1 to 367 residues) using RLGRDKYKTLRQIRQ as substrate in presence of ATP incubated for 40 mins by radiometric b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed