BDBM50576385 CHEMBL4854400

SMILES COc1cccc(CN2CC(C)(C)Oc3cc(ccc3C2=O)-c2ccc3[nH]ncc3c2)c1

InChI Key InChIKey=IIVFQRPDFQWYIO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576385   

TargetRho-associated protein kinase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50576385(CHEMBL4854400)
Affinity DataIC50: 749nMAssay Description:Inhibition of wild type partial length human ROCK1 (M1 to T431 residues) expressed in Mammalian expression system by Euro-fins kinase profiler assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50576385(CHEMBL4854400)
Affinity DataIC50: 6.01E+3nMAssay Description:Inhibition of wild type partial length human ROCK1 (M1 to R415 residues) expressed in mammalian expression system by Euro-fins kinase profiler assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed