BDBM50576322 CHEMBL4859922

SMILES CC(C)(O)[C@@H]1CC[C@H](CO1)NC(=O)c1ccc2nc(cn2c1)-c1ccccc1F

InChI Key InChIKey=UHTJVMDEKRCYRP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50576322   

TargetHematopoietic prostaglandin D synthase(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50576322(CHEMBL4859922)
Affinity DataIC50: 190nMAssay Description:Inhibition of HPGDS in rat RBL cells assessed as reduction in PGD2 formation using PGH2 as substrate by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHematopoietic prostaglandin D synthase(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50576322(CHEMBL4859922)
Affinity DataIC50: 12nMAssay Description:Inhibition of human HPGDS assessed as reduction in PGD2 formation using PGH2 as substrate by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed