BDBM50575782 CHEMBL4873913

SMILES CC(C)CCc1cc(ccc1O)C(=O)Nc1c(O)c2ccc(O)c(C)c2oc1=O

InChI Key InChIKey=JJEYPKKXPKNPIS-UHFFFAOYSA-N

Data  2 KI  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50575782   

TargetMicrotubule-associated proteins 1A/1B light chain 3B(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50575782(CHEMBL4873913)
Affinity DataKd:  2.16E+4nMAssay Description:Binding affinity to human LC3B expressed in Escherichia coli BL21-(DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMicrotubule-associated proteins 1A/1B light chain 3A(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50575782(CHEMBL4873913)
Affinity DataIC50: 1.19E+5nMAssay Description:Displacement of sGFP-p62-LIR peptide from human N-terminal SNAP-fused LC3A by time-resolved FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMicrotubule-associated proteins 1A/1B light chain 3A(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50575782(CHEMBL4873913)
Affinity DataKd:  1.42E+4nMAssay Description:Binding affinity to human LC3A expressed in Escherichia coli BL21-(DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMicrotubule-associated proteins 1A/1B light chain 3B(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50575782(CHEMBL4873913)
Affinity DataIC50: 2.51E+5nMAssay Description:Displacement of sGFP-p62-LIR peptide from human N-terminal SNAP-fused LC3B by time-resolved FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMicrotubule-associated proteins 1A/1B light chain 3A(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50575782(CHEMBL4873913)
Affinity DataKi:  2.43E+4nMAssay Description:Displacement of sGFP-p62-LIR peptide from human N-terminal SNAP-fused LC3A by time-resolved FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMicrotubule-associated proteins 1A/1B light chain 3B(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50575782(CHEMBL4873913)
Affinity DataKi:  2.81E+4nMAssay Description:Displacement of sGFP-p62-LIR peptide from human N-terminal SNAP-fused LC3B by time-resolved FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed