BDBM50575719 CHEMBL4859268

SMILES CC(C)(Cc1ccc(F)cc1)NC(=O)[C@H](CCC(O)=O)NC(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=JWQMTWCFNZSLNR-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50575719   

LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant ADAMTS5 using synthetic peptide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant ADAMTS4 using synthetic peptide as substrate by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 9.58E+3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 30nMAssay Description:Inhibition of ADAMTS-4 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 40nMAssay Description:Inhibition of ADAMTS-5 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of MMP12 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MMP13 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50575719(CHEMBL4859268)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MMP14 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed