BDBM50575489 CHEMBL4871711

SMILES N[C@H](CC(O)=O)Cn1nnc(n1)-c1ccc(Oc2ncc(Cl)cc2F)cc1

InChI Key InChIKey=ZEGMEJVULDALSH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50575489   

TargetLeukotriene A-4 hydrolase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50575489(CHEMBL4871711)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50575489(CHEMBL4871711)
Affinity DataIC50: 197nMAssay Description:Inhibition of LTA4H in human whole blood assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 15 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50575489(CHEMBL4871711)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]WIN35428 from recombinant human dopamine transporter by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed