BDBM50575359 CHEMBL4867186

SMILES NC1(CCN(CC1)c1ncnc2[nH]ccc12)C(=O)N[C@@H](C(=O)NO)c1ccccc1

InChI Key InChIKey=FLXCIQSKMFAMNL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575359   

TargetAminopeptidase N(Pig)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50575359(CHEMBL4867186)
Affinity DataIC50: 960nMAssay Description:Inhibition of APN in pig kidney microsomes assessed as reduction in p-nitroanilide release using L-leu-p-nitroanilide as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50575359(CHEMBL4867186)
Affinity DataIC50: 121nMAssay Description:Inhibition of AKT1 (unknown origin) incubated for 40 mins in presence of ATP by Kinase-Glo reagent based luminescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed