BDBM50575321 CHEMBL4851618

SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccc(O)c(I)c1)NC(=O)c1cc2c(F)cccc2[nH]1)C(O)=O

InChI Key InChIKey=ZJRVNTQPMGMJOH-UHFFFAOYSA-N

Data  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50575321   

TargetInterleukin-2(Human)
Philochem

Curated by ChEMBL
LigandPNGBDBM50575321(CHEMBL4851618)
Affinity DataKd:  340nMAssay Description:Binding affinity to L19-IL2 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAlbumin(Human)
Philochem

Curated by ChEMBL
LigandPNGBDBM50575321(CHEMBL4851618)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to human serum albumin by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Philochem

Curated by ChEMBL
LigandPNGBDBM50575321(CHEMBL4851618)
Affinity DataKd:  4.40E+3nMAssay Description:Binding affinity to TNF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetInterleukin-2(Human)
Philochem

Curated by ChEMBL
LigandPNGBDBM50575321(CHEMBL4851618)
Affinity DataIC50: 3.40E+3nMAssay Description:Binding affinity to IL2 (unknown origin) preincubated for 15 mins followed by NARA1 addition and measured after 1 hr in presence of NARA1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed