BDBM50575302 CHEMBL4847216

SMILES CNC(=O)c1ccc(c(C)n1)-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12

InChI Key InChIKey=MZFRLKHEVQGSLV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575302   

TargetPolycomb protein EED(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575302(CHEMBL4847216)
Affinity DataIC50: 8nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575302(CHEMBL4847216)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed