BDBM50575294 CHEMBL4855124

SMILES Cc1ncc(-c2cnc(NCc3c4CCOc4ccc3F)c3cn[nH]c(=O)c23)n1C

InChI Key InChIKey=RWESYWNGHMFWPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575294   

TargetPolycomb protein EED(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575294(CHEMBL4855124)
Affinity DataIC50: 13nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575294(CHEMBL4855124)
Affinity DataIC50: 13nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed