BDBM50575277 CHEMBL4851602

SMILES CN(c1ccncc1)c1cnc(NCc2c3CCOc3ccc2F)n2cnnc12

InChI Key InChIKey=VPJDUAGRGRUJTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575277   

TargetPolycomb protein EED(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575277(CHEMBL4851602)
Affinity DataIC50: 41nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575277(CHEMBL4851602)
Affinity DataIC50: 40nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed