BDBM50575265 CHEMBL4845889

SMILES Fc1ccc2OCCc2c1CNc1ncc(N2Cc3ccccc3OC2=O)c2nncn12

InChI Key InChIKey=KOYHUMIKYZIGGL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575265   

TargetPolycomb protein EED(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575265(CHEMBL4845889)
Affinity DataIC50: 45nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575265(CHEMBL4845889)
Affinity DataIC50: 45nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed