BDBM50575191 CHEMBL4846563

SMILES CC[C@H](C)[C@@H](NC(=O)[C@H](NC(=O)[C@H](NC(=O)C(C)(C)NC(=O)CNC(=O)[C@H](NC(=O)OC(C)(C)C)C(C)C)C(C)C)C(C)C)C(=O)NC(C)(C)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@H](C(C)C)C(=O)NC(C)(C)C(=O)OC

InChI Key InChIKey=SJGAOAJELVBEMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50575191   

TargetPresenilin-1(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50575191(CHEMBL4846563)
Affinity DataIC50: 35nMAssay Description:Inhibition of gamma secretase (unknown origin) expressed in HEK293 cells assessed as reduction of A-beta40 levels using C100-FLAG as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed