BDBM50575176 CHEMBL4869215

SMILES CC(C)C[C@H](NC(=O)N(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)C)Cc1ccccc1)C(=O)N[C@H](C(C)C)C(N)=O

InChI Key InChIKey=CHNSQRKXYCGXQK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50575176   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
University of Kansas

Curated by ChEMBL

LigandBDBM50575176(CHEMBL4869215)Copy SMILESCopy InChI

Affinity DataIC50: 41nMAssay Description:Inhibition of gamma secretase (unknown origin) expressed in HEK293 cells assessed as reduction of A-beta40 levels using C100-FLAG as substrate incuba...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2022
Entry Details Article
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