BDBM50575103 CHEMBL4849582
SMILES COc1cc(OC)c(\C=C\[N+]([O-])=O)c(\C=C\c2ccc(NC(=O)C3CC3)cc2)c1
InChI Key InChIKey=RGZUNRLNIINAOD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50575103
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-stimulated mouse bone marrow-derived macrophages assessed as reduction in IL-1beta secretion prein...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataKd: 263nMAssay Description:Binding affinity to His-GFP fused tagged NLRP3 (unknown origin) expressed in HEK293T incubated for 30 mins by microscale thermophoresis assayMore data for this Ligand-Target Pair