BDBM50575060 CHEMBL4877857

SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1ccc2nc(Nc3ccc(cc3NC(=O)C=C)S(C)(=O)=O)ncc2c1

InChI Key InChIKey=GHHZJQUAHVVLOV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50575060   

TargetFibroblast growth factor receptor 4(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50575060(CHEMBL4877857)
Affinity DataIC50: 33nMAssay Description:Inhibition of N-terminal GST fusion tagged human FGFR4 cytoplasmic domain (460 to 802 end residues) expressed in baculovirus expression system preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50575060(CHEMBL4877857)
Affinity DataIC50: 28nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50575060(CHEMBL4877857)
Affinity DataIC50: 15nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50575060(CHEMBL4877857)
Affinity DataIC50: 102nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed