BDBM50575058 CHEMBL4879303

SMILES COc1cc(OC)c(Cl)c(c1Cl)-c1ccc2nc(Nc3ccc(SC)cc3NC(=O)C=C)ncc2c1

InChI Key InChIKey=XLHXAKNUXURIJF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50575058   

TargetFibroblast growth factor receptor 4(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50575058(CHEMBL4879303)
Affinity DataIC50: 30nMAssay Description:Inhibition of N-terminal GST fusion tagged human FGFR4 cytoplasmic domain (460 to 802 end residues) expressed in baculovirus expression system preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50575058(CHEMBL4879303)
Affinity DataIC50: 39nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50575058(CHEMBL4879303)
Affinity DataIC50: 24nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50575058(CHEMBL4879303)
Affinity DataIC50: 79nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed