BDBM50575023 CHEMBL4856950

SMILES CCS(=O)(=O)c1ccc(cc1)[C@@H](CC(=O)NC)C(=O)Nc2ccc(cc2)C(C(F)(F)F)(C(F)(F)F)O

InChI Key InChIKey=FQOWZQYVIFDJJK-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575023   

TargetNuclear receptor ROR-gamma(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50575023(CHEMBL4856950)Copy SMILESCopy InChI

Affinity DataIC50: 49nMAssay Description:Inverse agonist activity at human RORC2 assessed as inhibition of SRC1-derived coactivator peptide by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
8/23/2022
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50575023(CHEMBL4856950)Copy SMILESCopy InChI

Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
8/23/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL