BDBM50575018 CHEMBL4852138

SMILES CCS(=O)(=O)c1ccc(nc1)C(NC(=O)Cc1ccccc1)C(=O)Nc1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=JGXUGSQGAKFAQZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50575018   

TargetNuclear receptor ROR-gamma(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50575018(CHEMBL4852138)Copy SMILESCopy InChI

Affinity DataIC50: 97nMAssay Description:Inverse agonist activity at human RORC2 assessed as inhibition of SRC1-derived coactivator peptide by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2022
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50575018(CHEMBL4852138)Copy SMILESCopy InChI

Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL