BDBM50574937 CHEMBL4863259

SMILES CN[C@H](C)C(=O)N[C@H](C(=O)N1C[C@H](C[C@H]1C(=O)Nc1c(F)cccc1F)NC(=O)c1cnc(cn1)N1CCN(CCCOc2cc3ncnc(Nc4n[nH]c(C)c4C)c3cc2S(=O)(=O)C(C)(C)C)CC1)C(C)(C)C

InChI Key InChIKey=CHNBEZLJAQUZEX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50574937   

LigandPNGBDBM50574937(CHEMBL4863259)
Affinity DataIC50: 10nMAssay Description:Inhibition of full length His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescent labelled ATP competitive lig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50574937(CHEMBL4863259)
Affinity DataIC50: 6.31E+3nMAssay Description:Binding affinity to human His-thr XIAP BIR3 (241 to 356) domain expressed in Escherichia coli measured after 105 mins in dark by time-resolved fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50574937(CHEMBL4863259)
Affinity DataIC50: 79nMAssay Description:Binding affinity to human 6His-thr cIAP1 BIR3 (253 to 363) domain expressed in Escherichia coli measured after 105 mins in dark by time-resolved fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed