BDBM50574843 CHEMBL4873498

SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccncc1)\C=C(/F)S(=O)(=O)c1ccccc1

InChI Key InChIKey=VBHYQAVSSHIJNV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50574843   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50574843(CHEMBL4873498)
Affinity DataKi:  56nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50574843(CHEMBL4873498)
Affinity DataKi:  577nMAssay Description:Inhibition of human liver CatL assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorometric enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCathepsin B(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50574843(CHEMBL4873498)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human liver CatB assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate by fluorometric enzyme assaysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed