BDBM50574840 CHEMBL4851440

SMILES Cc1cccc(C[C@H](NC(=O)c2ccncc2)C(=O)N[C@@H](CCc2ccccc2)\C=C(/F)S(=O)(=O)c2ccccc2)c1

InChI Key InChIKey=CKHJKNONKYKGBK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50574840   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50574840(CHEMBL4851440)
Affinity DataKi:  25nMAssay Description:Inhibition of Trypanosoma brucei rhodesain assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Johannes Gutenberg University

Curated by ChEMBL
LigandPNGBDBM50574840(CHEMBL4851440)
Affinity DataKi:  49nMAssay Description:Inhibition of human liver CatL assessed as fluorescence using Cbz-Phe-Arg-AMC as substrate measured at second inhibition step by fluorometric enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed