BDBM50574655 CHEMBL4852896

SMILES Oc1ccc(F)c(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Sc2cccc(Cl)c2)cc1

InChI Key InChIKey=PJPJOMRWQMCFNU-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50574655   

TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50574655(CHEMBL4852896)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant MAGL using 4-NPA as substrate by microplate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetFatty acid 2-hydroxylase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50574655(CHEMBL4852896)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant FAAH using AMC arachidonoyl amyl as substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50574655(CHEMBL4852896)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human recombinant MAGL assessed as dissociation constant using 4-NPA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed