BDBM50574434 CHEMBL4861066

SMILES NCc1ccc(NC(=O)c2cc3ccccc3cc2O)cc1

InChI Key InChIKey=VRZLGSXKZZLNLO-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50574434   

TargetKallikrein-6(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574434(CHEMBL4861066)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of KLK6 (unknown origin) assessed as release of AMC fluorescent product using Boc-QAR-AMC as substrate incubated for 30 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPlasminogen(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574434(CHEMBL4861066)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of plasmin (unknown origin) assessed as release of AMC fluorescent product using Boc-QAR-AMC as substrate incubated for 30 mins by micropl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574434(CHEMBL4861066)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of KLK1 (unknown origin) assessed as release of AMC fluorescent product using H-PFR-AMC as substrate incubated for 30 mins by microplate r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKallikrein-6(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574434(CHEMBL4861066)
Affinity DataKi:  800nMAssay Description:Non-competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPlasminogen(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574434(CHEMBL4861066)
Affinity DataKi:  1.30E+3nMAssay Description:Competitive inhibition of plasmin (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574434(CHEMBL4861066)
Affinity DataKi:  2.40E+3nMAssay Description:Competitive inhibition of KLK1 (unknown origin) assessed as release of AMC fluorescent product using H-PFR-AMC as substrate incubated for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed