BDBM50574432 CHEMBL4863108

SMILES CC(C)c1ccc(C(=O)Nc2ccc(CN)cc2)c(O)c1

InChI Key InChIKey=LERYNNIOTWZURB-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50574432   

TargetKallikrein-6(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574432(CHEMBL4863108)
Affinity DataIC50: 3.63E+3nMAssay Description:Inhibition of KLK6 (unknown origin) assessed as release of AMC fluorescent product using Boc-QAR-AMC as substrate incubated for 30 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPlasminogen(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574432(CHEMBL4863108)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of plasmin (unknown origin) assessed as release of AMC fluorescent product using Boc-QAR-AMC as substrate incubated for 30 mins by micropl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574432(CHEMBL4863108)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of KLK1 (unknown origin) assessed as release of AMC fluorescent product using H-PFR-AMC as substrate incubated for 30 mins by microplate r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKallikrein-6(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574432(CHEMBL4863108)
Affinity DataKi:  1.50E+3nMAssay Description:Competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed