BDBM50574431 CHEMBL4847066

SMILES Cc1ccc(C(=O)Nc2ccc(CN)cc2)c(O)c1

InChI Key InChIKey=GKPOHSSTLWSOGV-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50574431   

TargetKallikrein-6(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574431(CHEMBL4847066)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of KLK6 (unknown origin) assessed as release of AMC fluorescent product using Boc-QAR-AMC as substrate incubated for 30 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetPlasminogen(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574431(CHEMBL4847066)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of plasmin (unknown origin) assessed as release of AMC fluorescent product using Boc-QAR-AMC as substrate incubated for 30 mins by micropl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574431(CHEMBL4847066)
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of KLK1 (unknown origin) assessed as release of AMC fluorescent product using H-PFR-AMC as substrate incubated for 30 mins by microplate r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetKallikrein-6(Human)
Sorbonne Universit£

Curated by ChEMBL
LigandPNGBDBM50574431(CHEMBL4847066)
Affinity DataKi:  2.00E+3nMAssay Description:Competitive inhibition of KLK6 (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed